Synthesis of p nitroacetanilide
The organic compound p-nitroacetanilide is prepared from acetanilide through nitration. When acetanilide is treated with nitrating mixture that is a mixture of nitric acid and sulphuric acid p-nitroacetanilide is formed. Along with p-nitroacetanilide, o-nitroacetanilide is also formed as a minor product.
Which product is major in synthesis of p-nitroacetanilide from acetanilide?
In this electrophilic aromatic substitution reaction, the acetamido group (−NHCOCH3) directs the nitronium ion (+NO2) to the ortho and para positions of the aromatic ring. 6 Thus, nitration of acetanilide principally produces ortho- and para-nitroacetanilides, with the para compound being the major product.
How do you make para nitroaniline?
Dissolve 4.0 mL of aniline in 10 mL of acetic acid in a 100 mL round bottom flask. To this solution, add 5 mL of acetic anhydride and mix well by swirling. CAUTION: the reaction is exothermic and the flask becomes warm.
How can we separate p-nitroacetanilide from O-Nitroacetanilide in the crude sample?
Recrystallisation of p-nitroacetanilide. Dissolve the crude product obtained above in about 20 ml of methylated spirit. Warm to get a clear solution. Filter while hot and cool the filtrate in ice. o-Nitroacetanilide goes in the filtrate while p-nitroacetanilide is obtained as colourless crystals on the filter paper.
What is para nitro Acetanilide?
Para nitro acetanilide is defined as a chemical compound that is a derivative of nitro acetanilide prepared from the mixture of nitrating and acetanilide. … Other names of p-Nitroacetanilide can be given as p-Acetamido Nitrobenzene, N-(4-nitrophenyl) acetamide, N-Acetyl-4-nitroaniline, and p-Nitroacetanilide.
Is an electrophile in the preparation of p-nitroacetanilide from acetanilide?
Nitronium ion is the electrophile generates from fuming nitric acid in presence of fuming sulphuric acid. In the second step p-nitroaniline is prepared from p-nitro acetanilide due to hydrolysis of acetate ion from acetamido functional group in presence of concentrated sulphuric acid.
What is the Iupac name of p-nitroacetanilide?
Nitroacetanilide
| Names | |
|---|---|
| Preferred IUPAC name N-(4-Nitrophenyl)acetamide | |
| Other names p-Acetamidonitrobenzene; p-Nitroacetanilide; N-Acetyl-4-nitroaniline | |
| Identifiers | |
| CAS Number | 104-04-1 |
How do you separate p-nitroacetanilide?
Large crystals of p-nitroacetanilide is obtained. Filter the crystals through filter paper. The separated p-nitroacetanilide is washed with cold water in order to remove excess of acid. It is crystallized from ethyl alcohol.